About the Authors

Ellen Ordinario

Contributed equally to this work with: Ellen Ordinario, Hye-Jung Han

Affiliation Life Sciences Division, Lawrence Berkeley National Laboratory, University of California, Berkeley, California, United States of America

Hye-Jung Han

Contributed equally to this work with: Ellen Ordinario, Hye-Jung Han

Affiliation Life Sciences Division, Lawrence Berkeley National Laboratory, University of California, Berkeley, California, United States of America

Saori Furuta

Affiliation Life Sciences Division, Lawrence Berkeley National Laboratory, University of California, Berkeley, California, United States of America

Laura M. Heiser

Current address: Biomedical Engineering, Oregon Health & Science University, Portland, Oregon, United States of America

Affiliation Life Sciences Division, Lawrence Berkeley National Laboratory, University of California, Berkeley, California, United States of America

Lakshmi R. Jakkula

Affiliation Life Sciences Division, Lawrence Berkeley National Laboratory, University of California, Berkeley, California, United States of America

Francis Rodier

Current address: CRCHUM/Institut du Cancer de Montréal, Université de Montréal, Faculty of Medicine, Department of Radiology, Radio-Oncology and Nuclear Medicine, Montreal, Quebec, Canada

Affiliation Life Sciences Division, Lawrence Berkeley National Laboratory, University of California, Berkeley, California, United States of America

Paul T. Spellman

Current address: Biomedical Engineering, Oregon Health & Science University, Portland, Oregon, United States of America

Affiliation Life Sciences Division, Lawrence Berkeley National Laboratory, University of California, Berkeley, California, United States of America

Judith Campisi

Affiliations Life Sciences Division, Lawrence Berkeley National Laboratory, University of California, Berkeley, California, United States of America, Buck Institute for Research on Aging, Novato, California, United States of America

Joe W. Gray

Current address: Biomedical Engineering, Oregon Health & Science University, Portland, Oregon, United States of America

Affiliation Life Sciences Division, Lawrence Berkeley National Laboratory, University of California, Berkeley, California, United States of America

Mina J. Bissell

Affiliation Life Sciences Division, Lawrence Berkeley National Laboratory, University of California, Berkeley, California, United States of America

Yoshinori Kohwi

Affiliation Life Sciences Division, Lawrence Berkeley National Laboratory, University of California, Berkeley, California, United States of America

Terumi Kohwi-Shigematsu

TKohwi-Shigematsu@lbl.gov

Affiliation Life Sciences Division, Lawrence Berkeley National Laboratory, University of California, Berkeley, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TKS YK HJH EO. Performed the experiments: EO HJH YK SF LMH LRJ. Analyzed the data: EO HJH MJB SF JWG JC LMH PTS YK TKS. Contributed materials: FR SF JC JWG MJB YK TKS. Wrote the paper: EO HJH SF MJB JC TKS.