About the Authors

Hiroko Shimada

Affiliation Department of Orthopedic Surgery, School of Medicine, Keio University, Tokyo, Japan

Yohei Okada

Contributed equally to this work with: Yohei Okada, Hideyuki Okano

yohei@a6.keio.jp (YO); hidokano@a2.keio.jp (HO)

Affiliations Department of Physiology, School of Medicine, Keio University, Tokyo, Japan, Kanrinmaru Project, School of Medicine, Keio University, Tokyo, Japan

Keiji Ibata

Affiliation Department of Physiology, School of Medicine, Keio University, Tokyo, Japan

Hayao Ebise

Affiliation Genomic Science Laboratories, Dainippon Sumitomo Pharma Co. Ltd., Osaka, Japan

Shin-ichi Ota

Affiliation Genomic Science Laboratories, Dainippon Sumitomo Pharma Co. Ltd., Osaka, Japan

Ikuo Tomioka

Current address: Department of Neurophysiology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan

Affiliation Marmoset Research Department, Central Institute for Experimental Animals, Kanagawa, Japan

Toshihiro Nomura

Affiliations Department of Physiology, School of Medicine, Keio University, Tokyo, Japan, Department of Pediatrics, School of Medicine, Keio University, Tokyo, Japan

Takuji Maeda

Affiliations Department of Physiology, School of Medicine, Keio University, Tokyo, Japan, Marmoset Research Department, Central Institute for Experimental Animals, Kanagawa, Japan

Kazuhisa Kohda

Affiliation Department of Physiology, School of Medicine, Keio University, Tokyo, Japan

Michisuke Yuzaki

Affiliation Department of Physiology, School of Medicine, Keio University, Tokyo, Japan

Erika Sasaki

Affiliations Department of Physiology, School of Medicine, Keio University, Tokyo, Japan, Marmoset Research Department, Central Institute for Experimental Animals, Kanagawa, Japan

Masaya Nakamura

Affiliation Department of Orthopedic Surgery, School of Medicine, Keio University, Tokyo, Japan

Hideyuki Okano

Contributed equally to this work with: Yohei Okada, Hideyuki Okano

yohei@a6.keio.jp (YO); hidokano@a2.keio.jp (HO)

Affiliation Department of Physiology, School of Medicine, Keio University, Tokyo, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HS YO MN HO. Performed the experiments: HS YO HE KI TN KK. Analyzed the data: HS YO HE SO KI TN KK MY. Contributed reagents/materials/analysis tools: HS YO HE SO KI TN KK MY IT TM ES. Wrote the paper: HS YO HE SO KI KK MY ES MN HO.