About the Authors

Nobuaki Shindoh

Contributed equally to this work with: Nobuaki Shindoh, Akinori Yoda, Yuka Yoda

Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Drug Discovery Research, Astellas Pharma Inc., Tsukuba, Ibaraki, Japan

Akinori Yoda

Contributed equally to this work with: Nobuaki Shindoh, Akinori Yoda, Yuka Yoda

Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

Yuka Yoda

Contributed equally to this work with: Nobuaki Shindoh, Akinori Yoda, Yuka Yoda

Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

Timothy J. Sullivan

Affiliation Microarray Core, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

Oliver Weigert

Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

Andrew A. Lane

Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

Nadja Kopp

Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

Liat Bird

Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

Scott J. Rodig

Affiliations Harvard Medical School, Boston, Massachusetts, United States of America, Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

Edward A. Fox

Affiliations Microarray Core, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

David M. Weinstock

dweinstock@partners.org

Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

Competing Interests

The authors have read the journal's policy and have the following conflicts: NS is an employee of Astellas, Inc. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials. The remaining authors declare no competing financial interests.

Author Contributions

Conceived and designed the experiments: NS AY DMW. Performed the experiments: NS AY YY OW AAL NK LB SJR. Analyzed the data: NS AY TJS EAF SJR DMW. Contributed reagents/materials/analysis tools: SJR. Wrote the paper: NS DMW.