About the Authors

Sangita M. Baxi

Affiliation Oncology Research, Pfizer Worldwide Research and Development, San Diego, California, United States of America

Wei Tan

Affiliation Oncology Research, Pfizer Worldwide Research and Development, San Diego, California, United States of America

Sean T. Murphy

Affiliation Medicinal Chemistry, Pfizer Worldwide Research and Development, San Diego, California, United States of America

Tod Smeal

Affiliation Oncology Research, Pfizer Worldwide Research and Development, San Diego, California, United States of America

Min-Jean Yin

min-jean.yin@pfizer.com

Affiliation Oncology Research, Pfizer Worldwide Research and Development, San Diego, California, United States of America

Competing Interests

Authors are employees and stock holders of Pfizer, Inc. There are no other relevant declarations relating to employment, consultancy, patents, products in development or marketed products. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MJY SMB TS. Performed the experiments: MJY SMB WT. Analyzed the data: SMB WT MJY. Contributed reagents/materials/analysis tools: MJY STM. Wrote the paper: SMB MJY.