About the Authors

Christian Eitzinger

Affiliation Department of Hygiene, Microbiology and Social Medicine, Division of Hygiene and Medical Microbiology, Innsbruck Medical University, Innsbruck, Austria

Silvia Ehrlenbach

Affiliation Department of Hygiene, Microbiology and Social Medicine, Division of Hygiene and Medical Microbiology, Innsbruck Medical University, Innsbruck, Austria

Herbert Lindner

Affiliation Division of Clinical Biochemistry, Biocenter, Innsbruck Medical University, Innsbruck, Austria

Leopold Kremser

Affiliation Division of Clinical Biochemistry, Biocenter, Innsbruck Medical University, Innsbruck, Austria

Waldemar Gottardi

Affiliation Department of Hygiene, Microbiology and Social Medicine, Division of Hygiene and Medical Microbiology, Innsbruck Medical University, Innsbruck, Austria

Dmitri Debabov

Affiliation NovaBay Pharmaceuticals, Inc., Emeryville, California, United States of America

Mark Anderson

Affiliation NovaBay Pharmaceuticals, Inc., Emeryville, California, United States of America

Markus Nagl

Contributed equally to this work with: Markus Nagl, Dorothea Orth

m.nagl@i-med.ac.at

Affiliation Department of Hygiene, Microbiology and Social Medicine, Division of Hygiene and Medical Microbiology, Innsbruck Medical University, Innsbruck, Austria

Dorothea Orth

Contributed equally to this work with: Markus Nagl, Dorothea Orth

Affiliation Department of Hygiene, Microbiology and Social Medicine, Division of Hygiene and Medical Microbiology, Innsbruck Medical University, Innsbruck, Austria

Competing Interests

Dmitri Debabov and Mark Anderson are employed by and Markus Nagl was a consultant for NovaBay Pharmaceuticals, Inc., the funder of this study. In this study, pure NVC-612 (molecular weight 209.63 g/mol) and NVC-422 (molecular weight 244.07 g/mol) were from NovaBay Pharmaceuticals Inc. There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: CE SE HL WG DD MA MN DO. Performed the experiments: CE SE LK. Analyzed the data: CE HL LK DD MN DO. Contributed reagents/materials/analysis tools: HL MN DO. Wrote the paper: CE SE MN DO. Critically revised the data: CE SE HL LK WG DD MA MN DO. Critically revised the manuscript: CE SE HL LK WG DD MA MN DO. Final approval of the manuscript: CE SE HL LK WG DD MA MN DO.