About the Authors

Dana M. Brantley-Sieders

Affiliation Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Kang-Hsien Fan

Affiliations Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Sandra L. Deming-Halverson

Affiliations Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Social & Scientific Systems, Inc., Durham, North Carolina, United States of America

Yu Shyr

Affiliations Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Vanderbilt-Ingram Comprehensive Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Rebecca S. Cook

rebecca.cook@Vanderbilt.Edu

Affiliations Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Vanderbilt-Ingram Comprehensive Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Competing Interests

Sandra L. Deming is employed by Social & Scientific Systems, Inc. This does not alter the authors' adherence to all PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: DBS KHF SLD YS RSC. Performed the experiments: KHF RSC. Analyzed the data: DBS KHF SLD YS RSC. Contributed reagents/materials/analysis tools: DBS KHF SLD YS RSC. Wrote the paper: DBS KHF SLD YS RSC.