About the Authors

Xin Cai

Contributed equally to this work with: Xin Cai, Li Li

Affiliation Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, Missouri, United States of America

Li Li

Contributed equally to this work with: Xin Cai, Li Li

Current address: Wellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

Affiliation Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, Missouri, United States of America

Arie Krumholz

Affiliation Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, Missouri, United States of America

Zijian Guo

Affiliation Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, Missouri, United States of America

Todd N. Erpelding

Affiliation Philips Research North America, Briarcliff Manor, New York, United States of America

Chi Zhang

Affiliation Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, Missouri, United States of America

Yu Zhang

Current address: Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia, United States of America

Affiliation Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, Missouri, United States of America

Younan Xia

Current address: Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia, United States of America

Affiliation Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, Missouri, United States of America

Lihong V. Wang

lhwang@biomed.wustl.edu

Affiliation Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, Missouri, United States of America

Competing Interests

The authors have read the journal’s policy and have the following conflicts: LVW has a financial interest in Microphotoacoustics, Incorporated, and Endra, Incorporated. Todd N. Erpelding is an employee of Philips Research North America. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors. The other authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LL XC AK LVW. Performed the experiments: LL XC AK ZG TNE CZ. Analyzed the data: XC LL. Contributed reagents/materials/analysis tools: YZ YX. Wrote the paper: XC LL LVW.