About the Authors

Daniel Hänggi

daniel.haenggi@uni-duesseldorf.de

Affiliation Department of Neurosurgery, Heinrich-Heine-University, Düsseldorf, Germany

Jason Perrin

Affiliation Department of Neurosurgery, Heinrich-Heine-University, Düsseldorf, Germany

Sven Eicker

Affiliation Department of Neurosurgery, Heinrich-Heine-University, Düsseldorf, Germany

Kerim Beseoglu

Affiliation Department of Neurosurgery, Heinrich-Heine-University, Düsseldorf, Germany

Nima Etminan

Affiliation Department of Neurosurgery, Heinrich-Heine-University, Düsseldorf, Germany

Marcel Alexander Kamp

Affiliation Department of Neurosurgery, Heinrich-Heine-University, Düsseldorf, Germany

Hi-Jae Heiroth

Affiliation Department of Neurosurgery, Heinrich-Heine-University, Düsseldorf, Germany

Nadia Bege

Affiliation Department of Pharmaceutics and Biopharmacy, Philipps-University, Marburg, Germany

Stephan Macht

Affiliation Institute of Neuroradiology, Heinrich-Heine-University, Düsseldorf, Germany

Katrin Frauenknecht

Affiliation Department of Neuropathology, University Medical Center of the Johannes-Gutenberg-University, Mainz, Germany

Clemens Sommer

Affiliation Department of Neuropathology, University Medical Center of the Johannes-Gutenberg-University, Mainz, Germany

Thomas Kissel

Affiliation Department of Pharmaceutics and Biopharmacy, Philipps-University, Marburg, Germany

Hans-Jakob Steiger

Affiliation Department of Neurosurgery, Heinrich-Heine-University, Düsseldorf, Germany

Competing Interests

Daniel Hänggi is a scientific advisor for Edge Therapeutics Inc. (New Providence, New Jersey, United States of America). This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: DH JP SOE NE MAK NB SM TK HJS. Performed the experiments: DH JP SOE NE MAK HH NB SM. Analyzed the data: KB KF CS TK. Contributed reagents/materials/analysis tools: NB TK. Wrote the paper: DH NE HJS TK CS.