About the Authors
- Mario Hermann
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Affiliations Institute of Laboratory Animal Science, University of Zurich, Zurich, Switzerland, Institute of Neuropathology, University Hospital Zurich, Zurich, Switzerland
- Morgan L. Maeder
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Affiliation Molecular Pathology Unit, Center for Cancer Research, and Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America
- Kyle Rector
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Affiliation Transposagen Biopharmaceuticals, Inc., Lexington, Kentucky, United States of America
- Joseph Ruiz
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Affiliation Transposagen Biopharmaceuticals, Inc., Lexington, Kentucky, United States of America
- Burkhard Becher
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Affiliation Institute for Experimental Immunology, University of Zurich, Zurich, Switzerland
- Kurt Bürki
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Affiliation Institute of Laboratory Animal Science, University of Zurich, Zurich, Switzerland
- Cyd Khayter
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Affiliation Molecular Pathology Unit, Center for Cancer Research, and Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America
- Adriano Aguzzi
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Affiliation Institute of Neuropathology, University Hospital Zurich, Zurich, Switzerland
- J. Keith Joung
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Affiliations Molecular Pathology Unit, Center for Cancer Research, and Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America
- Thorsten Buch
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Contributed equally to this work with: Thorsten Buch, Pawel Pelczar
* E-mail: thorsten.buch@mikrobio.med.tum.de (TB); pawel.pelczar@ltk.uzh.ch (PP)
Affiliations Institute for Experimental Immunology, University of Zurich, Zurich, Switzerland, Institute for Medical Microbiology, Immunology, and Hygiene, Technische Universität München, Munich, Germany
- Pawel Pelczar
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Contributed equally to this work with: Thorsten Buch, Pawel Pelczar
* E-mail: thorsten.buch@mikrobio.med.tum.de (TB); pawel.pelczar@ltk.uzh.ch (PP)
Affiliation Institute of Laboratory Animal Science, University of Zurich, Zurich, Switzerland
Competing Interests
KR and JR are employees of Transposagen Biopharmaceuticals, Inc. JKJ has a financial interest in Transposagen Biopharmaceuticals, Inc. JKJ's interests were reviewed and are managed by Massachusetts General Hospital and Partners HealthCare in accordance with their conflict of interest policies. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: TB PP JKJ. Performed the experiments: MH TB PP MLM KR JR CK. Analyzed the data: MH TB PP. Contributed reagents/materials/analysis tools: AA BB KB KR JR. Wrote the paper: TB PP MH . Supervision of Experiments: TB PP AA BB KB JKJ.