About the Authors

Shunichi Fukuhara


Affiliation Department of Healthcare Epidemiology, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Tadao Akizawa

Affiliation Division of Nephrology, Department of Medicine, School of Medicine, Showa University, Tokyo, Japan

Satoshi Morita

Affiliation Department of Biostatistics and Epidemiology, School of Medicine, University Medical Center, Yokohama City University, Yokohama, Japan

Yoshiharu Tsubakihara

Affiliation Department of Kidney Disease and Hypertension, Osaka General Medical Center, Osaka, Japan

Competing Interests

The authors' have read the journal's policy and have the following conflicts: The data used in this study were collected as part of a trial sponsored by Kyowa Hakko Kirin Co., Ltd (Tokyo, Japan). The authors participated in that trial as advisers and received consultation fees from Kyowa Hakko Kirin Co., Ltd. This does not alter the authors‘ adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SF SM. Performed the experiments: TA YT. Analyzed the data: SF SM. Wrote the paper: SF. Gave advice regarding results from the preceding clinical trial: TA YT.