About the Authors

Manish J. Butte

Contributed equally to this work with: Manish J. Butte, Sun Jung Lee

Current address: Department of Pediatrics, Division of Immunology and Allergy, Stanford University, Stanford, California, United States of America

Affiliation Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America

Sun Jung Lee

Contributed equally to this work with: Manish J. Butte, Sun Jung Lee

Affiliation Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America

Jonathan Jesneck

Affiliation Department of Pediatric Oncology, Dana Farber Cancer Institute, Boston, Massachusetts, United States of America and Division of Pediatric Hematology/Oncology, Children’s Hospital, Boston, Massachusetts, United States of America

Mary E. Keir

Current address: Genentech, South San Francisco, California, United States of America

Affiliation Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America

W. Nicholas Haining

Affiliation Department of Pediatric Oncology, Dana Farber Cancer Institute, Boston, Massachusetts, United States of America and Division of Pediatric Hematology/Oncology, Children’s Hospital, Boston, Massachusetts, United States of America

Arlene H. Sharpe

arlene_sharpe@hms.harvard.edu

Affiliations Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Pathology, Brigham and Women’s Hospital, Boston, Massachusetts, United States of America

Competing Interests

The authors have no conflicting financial interests. Dr. Mary Keir is currently employed by Genentech. This does not alter the authors’ adherence to all of the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MJB SJL AHS. Performed the experiments: MJB SJL MEK. Analyzed the data: MJB SJL AHS. Contributed reagents/materials/analysis tools: MJB SJL JJ MEK WNH. Wrote the paper: MJB SJL WNH AHS.