About the Authors

Hae-Jung Park

Affiliation International Vaccine Institute, Seoul, Korea

Boris Ferko

Affiliation AVIR Green Hills Biotechnology AG, Vienna, Austria

Young-Ho Byun

Affiliation Department of Biotechnology and Translational Research Center for Protein Function Control, Yonsei University, Seoul, Korea

Joo-Hye Song

Affiliation International Vaccine Institute, Seoul, Korea

Gye-Yeong Han

Affiliation International Vaccine Institute, Seoul, Korea

Elisabeth Roethl

Affiliation AVIR Green Hills Biotechnology AG, Vienna, Austria

Andrej Egorov

Affiliation AVIR Green Hills Biotechnology AG, Vienna, Austria

Thomas Muster

Affiliation AVIR Green Hills Biotechnology AG, Vienna, Austria

Baiklin Seong

Affiliation Department of Biotechnology and Translational Research Center for Protein Function Control, Yonsei University, Seoul, Korea

Mi-Na Kweon

Affiliation International Vaccine Institute, Seoul, Korea

Manki Song

Affiliation International Vaccine Institute, Seoul, Korea

Cecil Czerkinsky

Affiliation International Vaccine Institute, Seoul, Korea

Huan H. Nguyen

hhnguyen@ivi.int

Affiliation International Vaccine Institute, Seoul, Korea

Competing Interests

BF, ER, AE, and TM were employees of Avir Green Hills Biotechnology (AGHB) AG, Vienna, Austria at the time of study. IPR rights related to this manuscript are covered by the following IP rights: DelNs1 mutants are covered by patents from AGHB and Mount Sinai School of Medicine. Patent applications covering the technology platform of the influenza virus and virus amplification procedure are fully owned by AGHB (US 8,057,803 B2 and the publication day is Feb. 26, 2009.) In adherence to the PLoS guidelines, AGHB will make freely available any materials and information described in the publication that are reasonably requested by others for the purpose of academic, non-commercial research. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: HHN CC BF AE. Performed the experiments: HJP YHB JHS GYH BF ER. Analyzed the data: HHN HJP BF AE CC MKS TM. Contributed reagents/materials/analysis tools: MNK BS MKS TM. Wrote the paper: HHN HJP CC BF AE.