About the Authors

Haruka Tamura

Affiliation Unit of Environmental Health Sciences, Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, Kasugai, Aichi, Japan

Nobutaka Ohgami

Affiliation Unit of Environmental Health Sciences, Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, Kasugai, Aichi, Japan

Ichiro Yajima

Affiliation Unit of Environmental Health Sciences, Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, Kasugai, Aichi, Japan

Machiko Iida

Affiliation Unit of Environmental Health Sciences, Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, Kasugai, Aichi, Japan

Kyoko Ohgami

Affiliation Unit of Environmental Health Sciences, Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, Kasugai, Aichi, Japan

Noriko Fujii

Affiliation Research Reactor Institute, Kyoto University, Kumatori-cho, Sennan, Osaka, Japan

Hiroyuki Itabe

Affiliation Department of Biological Chemistry, Showa University School of Pharmacy, Hatanodai, Shinagawa-ku, Tokyo, Japan

Tastuya Kusudo

Affiliation Unit of Molecular Biology, Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, Kasugai, Aichi, Japan

Hitoshi Yamashita

Affiliation Unit of Molecular Biology, Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, Kasugai, Aichi, Japan

Masashi Kato

katomasa@isc.chubu.ac.jp

Affiliation Unit of Environmental Health Sciences, Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, Kasugai, Aichi, Japan

Competing Interests

Mitsui & Co., Ltd. was a commercial funder of this study. This does not alter the authors’ adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: NO HT MK. Performed the experiments: HT NO KO. Analyzed the data: HT NO MK. Contributed reagents/materials/analysis tools: IY MI NF HI TK HY. Wrote the paper: HT NO MK.