About the Authors

Elias Cesar Araujo de Carvalho

Affiliations Research on Research Group, Department of Surgery, Duke University, Durham, North Carolina, United States of America, Cesumar, Universitary Center of Maringa, Paraná, Brazil, UEM, State University of Maringa, Paraná, Brazil

Adelia Portero Batilana

Affiliation Research on Research Group, Department of Surgery, Duke University, Durham, North Carolina, United States of America

Wederson Claudino

Affiliation Oncologistas Associados Cancer Institute, Rio de Janeiro, Brazil

Luiz Fernando Lima Reis

Affiliation Institute for Teaching and Research, Sirio Libanes Hospital, São Paulo, Brasil

Rafael A. Schmerling

Affiliation Institute for Teaching and Research, Sirio Libanes Hospital, São Paulo, Brasil

Jatin Shah

Affiliations Research on Research Group, Duke-NUS Graduate Medical School, Singapore, Singapore, Research on Research Group, Duke University, Durham, North Carolina, United States of America

Ricardo Pietrobon

rpietro@duke.edu

Affiliations Department of Surgery, Duke University Health System, Durham, North Carolina, United States of America, Duke - NUS Graduate Medical School, Singapore, Singapore, Research on Research Group, Duke University, Durham, North Carolina, United States of America

Competing Interests

This study was funded by Sanofi Aventis, with Mr. Carvalho and Batilana being directly compensated as consultants. Dr. Claudino is currently conducting clinical trials with Sanofi-Aventis. Dr. Reis is Chief Scientific Officer of CRC Sao Paulo. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: EC AB WC LFLR JS RP. Performed the experiments: EC AB RP. Analyzed the data: EC AB RP. Wrote the paper: EC AB WC LFLR JS RP RAS.