About the Authors

Megan S. C. Lim

Affiliation Research Department of Infection and Population Health, University College London, London, United Kingdom

Robert J. Dowdeswell

Affiliation Rustenburg Platinum Mines Limited, Rustenburg, South Africa

Jill Murray

Affiliation National Institute for Occupational Health, National Health Laboratory Service and School of Public Health, University of the Witwatersrand, Johannesburg, South Africa

Nigel Field

Affiliation Research Department of Infection and Population Health, University College London, London, United Kingdom

Judith R. Glynn

Affiliation Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom

Pam Sonnenberg

p.sonnenberg@ucl.ac.uk

Affiliation Research Department of Infection and Population Health, University College London, London, United Kingdom

Competing Interests

The authors have the following interests: RD is an employee of Rustenburg Platinum Mines Limited and a part-time consultant to Anglo Platinum Ltd. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLoS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: ML RD JM NF JG PS. Performed the experiments: ML RD JM PS. Analyzed the data: ML RD JM NF JG PS. Contributed reagents/materials/analysis tools: ML RD JM NF JG PS. Wrote the paper: ML RD JM NF JG PS. Designed and conducted the analysis and literature review and drafted the manuscript: ML. Collated the data, assigned vital status, assisted in assigning cause of death, and contributed to the design and analysis of the study: RD. Contributed to the study design and manuscript preparation, collated the autopsy data, assisted in assigning cause of death, and the manuscript: JM. Assisted with literature review, study design and manuscript: NF. Contributed to the study design, analysis, and manuscript: JG. Contributed to the study design, assignment of cause of death, and the manuscript: PS.