About the Authors

Finola E. Moore

Affiliations Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Harvard Stem Cell Institute, Boston, Massachusetts, United States of America, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

Deepak Reyon

Affiliations Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America, Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America

Jeffry D. Sander

Affiliations Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America, Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America

Sarah A. Martinez

Affiliations Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Harvard Stem Cell Institute, Boston, Massachusetts, United States of America, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

Jessica S. Blackburn

Affiliations Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Harvard Stem Cell Institute, Boston, Massachusetts, United States of America, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

Cyd Khayter

Affiliations Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America, Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America

Cherie L. Ramirez

Affiliations Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America, Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America

J. Keith Joung

Affiliations Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America, Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America

David M. Langenau

dlangenau@partners.org

Affiliations Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Harvard Stem Cell Institute, Boston, Massachusetts, United States of America, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: FEM DML JDS DR JKJ. Performed the experiments: FEM DR SAM. Analyzed the data: FEM DML DR JDS JSB CLR JKJ. Contributed reagents/materials/analysis tools: FEM DML DR JSB CK CLR JKJ. Wrote the paper: FEM DML JDS DR JKJ.