About the Authors

Martin C. Herzig

Affiliation Department of Neuroscience, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland

Michael Bidinosti

Affiliation Department of Neuroscience, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland

Tatjana Schweizer

Affiliation Department of Neuroscience, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland

Thomas Hafner

Affiliation Department of Neuroscience, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland

Christine Stemmelen

Affiliation Department of Neuroscience, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland

Andreas Weiss

Affiliation Department of Neuroscience, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland

Simone Danner

Affiliation Department of Neuroscience, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland

Nella Vidotto

Affiliation Department of Neuroscience, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland

Daniela Stauffer

Affiliation Department of Neuroscience, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland

Carmen Barske

Affiliation Department of Neuroscience, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland

Franziska Mayer

Affiliation Department of Neuroscience, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland

Peter Schmid

Affiliation Department of Neuroscience, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland

Giorgio Rovelli

Affiliation Department of Neuroscience, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland

P. Herman van der Putten

Affiliation Department of Neuroscience, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland

Derya R. Shimshek

derya.shimshek@novartis.com

Affiliation Department of Neuroscience, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland

Competing Interests

All authors are employees of Novartis Pharma AG who funded this study. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all PLoS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: MCH MB AW PS GR PHvdP DRS. Performed the experiments: MCH MB TS TH CS SD NV DS CB FM DRS. Analyzed the data: MCH MB TS TH CS SD CB PS GR DRS. Wrote the paper: MCH MB PS GR PHvdP DRS.