About the Authors

Lauren E. Seber

Affiliations James Graham Brown Cancer Center, University of Louisville, Louisville, Kentucky, United States of America, Owensboro Cancer Research Program, Owensboro, Kentucky, United States of America

Brian W. Barnett

Current address: BASF Plant Science, L.P., Research Triangle Park, North Carolina, United States of America

Affiliation Owensboro Cancer Research Program, Owensboro, Kentucky, United States of America

Elizabeth J. McConnell

Affiliation Owensboro Cancer Research Program, Owensboro, Kentucky, United States of America

Steven D. Hume

Affiliation Kentucky BioProcessing, LLC, Owensboro, Kentucky, United States of America

Jian Cai

Affiliation Department of Pharmacology and Toxicology, University of Louisville, Louisville, Kentucky, United States of America

Kati Boles

Affiliation Owensboro Cancer Research Program, Owensboro, Kentucky, United States of America

Keith R. Davis

keith.davis@louisville.edu

Affiliations James Graham Brown Cancer Center, University of Louisville, Louisville, Kentucky, United States of America, Owensboro Cancer Research Program, Owensboro, Kentucky, United States of America, Department of Pharmacology and Toxicology, University of Louisville, Louisville, Kentucky, United States of America

Competing Interests

Portions of this research were funded by Owensboro Grain Company, LLC. Owensboro Grain Company was not involved in the performance or reporting of the described research. SDH is an employee of Kentucky BioProcessing, LLC, and KRD serves on the Board of Directors of Kentucky BioProcessing; KRD does not receive any compensation for this service. LES, BWB, and KRD are listed as inventors on a patent application that includes some of the data presented in this manuscript. These authors may benefit financially if the technology described in this patent is licensed or sold. There are no further products in development or marketed products to declare. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: BWB SDH KRD. Performed the experiments: LES BWB EJM SDH JC KB. Analyzed the data: LES EJM SDH JC KB KRD. Wrote the paper: KRD LES EJM JC KB.