About the Authors

Daisuke Nishi

Affiliations Department of Psychiatry, National Disaster Medical Center, Tachikawa, Japan, Clinical Research Institute, National Disaster Medical Center, Tachikawa, Japan, CREST, Japan Science and Technology Agency, Tachikawa, Japan

Yuichi Koido

Affiliations Clinical Research Institute, National Disaster Medical Center, Tachikawa, Japan, Head Office, Japan Disaster Medical Assistance Team, Tachikawa, Japan

Naoki Nakaya

Affiliations CREST, Japan Science and Technology Agency, Tachikawa, Japan, Department of Nutrition and Dietetics, Faculty of Family and Consumer Science, Kamakura Women's University, Kamakura, Japan

Toshimasa Sone

Affiliations CREST, Japan Science and Technology Agency, Tachikawa, Japan, Department of Rehabilitation, Faculty of Health Science, Tohoku Fukushi University, Sendai, Japan

Hiroko Noguchi

Affiliations Clinical Research Institute, National Disaster Medical Center, Tachikawa, Japan, CREST, Japan Science and Technology Agency, Tachikawa, Japan, Department of Adult Mental Health, National Institute of Mental Health, National Center of Neurology and Psychiatry, Kodaira, Japan

Kei Hamazaki

Affiliations CREST, Japan Science and Technology Agency, Tachikawa, Japan, Department of Public Health, Faculty of Medicine, University of Toyama, Toyama, Japan

Tomohito Hamazaki

Affiliations CREST, Japan Science and Technology Agency, Tachikawa, Japan, Department of Clinical Sciences, Institute of Natural Medicine, University of Toyama, Toyama, Japan

Yutaka Matsuoka

yutaka@ncnp.go.jp

Affiliations Department of Psychiatry, National Disaster Medical Center, Tachikawa, Japan, Clinical Research Institute, National Disaster Medical Center, Tachikawa, Japan, CREST, Japan Science and Technology Agency, Tachikawa, Japan, Department of Adult Mental Health, National Institute of Mental Health, National Center of Neurology and Psychiatry, Kodaira, Japan, Clinical Research Training and Consultation Program, Translational Medical Center, National Center of Neurology and Psychiatry, Kodaira, Japan

Competing Interests

YM has received another research support from the Ministry of Health, Labor, and Welfare of Japan and a lecture fee from Eli Lilly Japan. DN has received research support from Toray Industries, Inc., and the Foundation for Total Health Promotion and a lecture fee from Qol Co., Ltd. KH has received research support from the Japan Society for the Promotion of Science, the Tamura Foundation for Promotion of Science and Technology, and the Ichiro Kanehara Foundation for Promotion of Medical Sciences and Medical Care, and consultant fees from Polyene Project, Inc., and Otsuka Pharmaceutical Co., Ltd., and a lecture fee from Nippon Suisan Kaisha, Ltd. TM has received research support from the Japan Society for the Promotion of Science, Open Research Center for Lipid Nutrition (Kinjo Gakuin University, and Nippon Suisan Kaisha, Ltd., and consultant fees from Polyene Project, Inc., and Otsuka Pharmaceutical Co., Ltd., and lecture fees from Mochida Pharmaceutical Co., Ltd.) YK has received research support from the Ministry of Health, Labor, and Welfare of Japan, Ono Pharmaceutical Co., Ltd., Astrazeneca K.K., Bristol-Myers Squibb Company, and National Center of Global Health and Medicine. All other authors declare that they have no competing interests. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: DN YM. Performed the experiments: DN YM. Analyzed the data: DN NN TS YM. Wrote the paper: DN YM. Drafted the original protocol: DN YM. Participated in the refinements of the protocol: DN YK NN TS KH TH YM. Managed the enrollment procedure and overall regulation of the study: YK. Commented on the drafts: YK NN TS HN KH TH.