About the Authors

Joël Lelièvre

Contributed equally to this work with: Joël Lelièvre, Maria Jesus Almela

Joel.l.lelievre@gsk.com (JL); esperanza.a.herreros@gsk.com (EH)

Affiliation GlaxoSmithKline R&D, Tres Cantos Medicine Development Campus, Malaria Discovery Performance Unit, Madrid, Spain

Maria Jesus Almela

Contributed equally to this work with: Joël Lelièvre, Maria Jesus Almela

Affiliation GlaxoSmithKline R&D, Tres Cantos Medicine Development Campus, Malaria Discovery Performance Unit, Madrid, Spain

Sonia Lozano

Affiliation GlaxoSmithKline R&D, Tres Cantos Medicine Development Campus, Malaria Discovery Performance Unit, Madrid, Spain

Celia Miguel

Affiliation GlaxoSmithKline R&D, Tres Cantos Medicine Development Campus, Malaria Discovery Performance Unit, Madrid, Spain

Virginia Franco

Current address: Centro de Biología Molecular (UAM-CSIC), Campus de la Universidad Autónoma de Madrid, Madrid, Spain

Affiliation GlaxoSmithKline R&D, Tres Cantos Medicine Development Campus, Malaria Discovery Performance Unit, Madrid, Spain

Didier Leroy

Affiliation Medicines for Malaria Venture, Geneva, Switzerland

Esperanza Herreros

Joel.l.lelievre@gsk.com (JL); esperanza.a.herreros@gsk.com (EH)

Affiliation GlaxoSmithKline R&D, Tres Cantos Medicine Development Campus, Malaria Discovery Performance Unit, Madrid, Spain

Competing Interests

The authors have read the journal's policy and have the following conflicts: JL SL MJA EH CM are employees of GlaxoSmithKline (GSK) and work was funded by GSK under a general research program. DL is employee of Medicines for Malaria Venture (MMV). This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials. Neither GSK nor MMV have influenced or biased the content of this work.

Author Contributions

Conceived and designed the experiments: JL MJA SL EH. Performed the experiments: JL MJA SL CM VF. Analyzed the data: JL MJA SL EH. Contributed reagents/materials/analysis tools: JL MJA SL CM VF. Wrote the paper: JL MJA EH DL.