About the Authors

Joshua J. Hamilton
Jennifer L. Reed

reed@engr.wisc.edu

Affiliation Department of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, Wisconsin, United States of America,

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JJH JLR. Performed the experiments: JJH. Analyzed the data: JJH JLR. Wrote the paper: JJH JLR. Conceived the mixed-integer programming approach: JJH JLR. Implemented the mixed-integer programming approach: JJH.