Tetrahydro iso-Alpha Acids from Hops Improve Glucose Homeostasis and Reduce Body Weight Gain and Metabolic Endotoxemia in High-Fat Diet-Fed Mice

Amandine Everard; Lucie Geurts; Marie Van Roye; Nathalie M. Delzenne; Patrice D. Cani

doi:10.1371/journal.pone.0033858

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Open Access

Peer-reviewed

Research Article

Tetrahydro iso-Alpha Acids from Hops Improve Glucose Homeostasis and Reduce Body Weight Gain and Metabolic Endotoxemia in High-Fat Diet-Fed Mice

Amandine Everard ,

Contributed equally to this work with: Amandine Everard, Lucie Geurts
⨯
Lucie Geurts ,

Contributed equally to this work with: Amandine Everard, Lucie Geurts
⨯
Marie Van Roye,
Nathalie M. Delzenne,
Patrice D. Cani

* E-mail: patrice.cani@uclouvain.be

Affiliation Université catholique de Louvain, Louvain Drug Research Institute, Metabolism and Nutrition Research Group, Brussels, Belgium
⨯

Tetrahydro iso-Alpha Acids from Hops Improve Glucose Homeostasis and Reduce Body Weight Gain and Metabolic Endotoxemia in High-Fat Diet-Fed Mice

Amandine Everard,
Lucie Geurts,
Marie Van Roye,
Nathalie M. Delzenne,
Patrice D. Cani

Published: March 28, 2012
https://doi.org/10.1371/journal.pone.0033858

About the Authors

Amandine Everard

Contributed equally to this work with: Amandine Everard, Lucie Geurts

Lucie Geurts

Contributed equally to this work with: Amandine Everard, Lucie Geurts

Marie Van Roye

Nathalie M. Delzenne

Patrice D. Cani

* E-mail: patrice.cani@uclouvain.be

Affiliation Université catholique de Louvain, Louvain Drug Research Institute, Metabolism and Nutrition Research Group, Brussels, Belgium

Competing Interests

This study was supported by Metagenics, Inc., United States of America. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials. The funder Metagenics, Inc., United States of America, have nothing to declare relating to employment, consultancy, patents, products in development or marketed products in this study.

Author Contributions

Conceived and designed the experiments: PDC. Performed the experiments: AE LG MVR PDC. Analyzed the data: AE LG NMD PDC. Contributed reagents/materials/analysis tools: NMD PDC. Wrote the paper: PDC. Provided intellectual input on the paper and reviewed the paper: AE LG NMD PDC.

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Diet and type 2 diabetes
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Obesity
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Type 2 diabetes
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Body weight
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Insulin resistance
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Glucose metabolism
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Endotoxemia
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Weight gain
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