About the Authors

Hanna Nohynek

hanna.nohynek@thl.fi

Affiliation Department of Vaccines and Immune Protection, National Institute for Health and Welfare, Helsinki, Finland

Jukka Jokinen

Affiliation Department of Vaccines and Immune Protection, National Institute for Health and Welfare, Helsinki, Finland

Markku Partinen

Affiliation Helsinki Sleep Clinic, Vitalmed Research Centre, Helsinki, Finland

Outi Vaarala

Affiliation Department of Vaccines and Immune Protection, National Institute for Health and Welfare, Helsinki, Finland

Turkka Kirjavainen

Affiliation Department of Pediatrics, Children's Hospital, Helsinki University Hospital, Helsinki, Finland

Jonas Sundman

Affiliation Department of Vaccines and Immune Protection, National Institute for Health and Welfare, Helsinki, Finland

Sari-Leena Himanen

Affiliation Department of Clinical Neurophysiology, Tampere University Hospital, Tampere, Finland

Christer Hublin

Affiliation Finnish Institute of Occupational Health, Helsinki, Finland

Ilkka Julkunen

Affiliation Department of Infectious Disease Surveillance and Control, National Institute for Health and Welfare, Helsinki, Finland

Päivi Olsén

Affiliation Department of Child Neurology, Oulu University Hospital, Oulu, Finland

Outi Saarenpää-Heikkilä

Affiliation Department of Pediatrics, Tampere University Hospital, Tampere, Finland

Terhi Kilpi

Affiliation Department of Vaccines and Immune Protection, National Institute for Health and Welfare, Helsinki, Finland

Competing Interests

HN received honoraria for technical consultancy from GlaxoSmithKline (GSK), and Pfizer for development of pneumococcal conjugate vaccines. JJ is co-investigator of a nationwide effectiveness study of the ten-valent pneumococcal conjugate vaccine mainly funded by GlaxoSmithKline. MP has been consultant for Bioprojet and UCB Pharma and received funding support and travel grants from Boehringer-Ingelheim, Bioprojet, GSK, Cephalin, MSD, Leiras and Servier. T. Kilpi is principal investigator of a nationwide effectiveness study of the ten-valent pneumococcal conjugate vaccine mainly funded by GlaxoSmithKline, and her unit received funding for a clinical trial on the safety and immunogenicity of a prototype pandemic influenza vaccine from Solvay Pharmaceuticals. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials. All other authors confirm they have no conflicts of interest.

Author Contributions

Conceived and designed the experiments: JJ T. Kilpi HN. Analyzed the data: JJ T. Kilpi HN. Contributed reagents/materials/analysis tools: JJ JS. Wrote the paper: HN JJ MP OV T. Kirjavainen JS SLH CH IJ PO OSH T. Kilpi. Designed the database: JJ JS. Obtained permissions: JJ HN T. Kilpi. Obtained data: JJ JS HN. Validated cases: MP T. Kirjavainen PO SLH OSH CH.