About the Authors

Takeo Iwata

Affiliation Department of Medical Pharmacology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan

Hisaaki Taniguchi

Affiliation Division of Disease Proteomics, Institute for Enzyme Research, The University of Tokushima, Tokushima, Japan

Masamichi Kuwajima

Affiliations Department of Clinical Biology and Medicine, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan, Taijukai-Kaisei General Hospital, Sakaide, Japan

Takako Taniguchi

Affiliation Division of Disease Proteomics, Institute for Enzyme Research, The University of Tokushima, Tokushima, Japan

Yuko Okuda

Affiliation Division of Disease Proteomics, Institute for Enzyme Research, The University of Tokushima, Tokushima, Japan

Akiko Sukeno

Affiliation Department of Clinical Biology and Medicine, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan

Kyoko Ishimoto

Affiliation Department of Orthodontics and Dentofacial Orthopedics, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan

Noriko Mizusawa

Affiliation Department of Medical Pharmacology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan

Katsuhiko Yoshimoto

yoshimot@dent.tokushima-u.ac.jp

Affiliation Department of Medical Pharmacology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TI KY. Performed the experiments: TI HT MK TT YO AS KI NM. Analyzed the data: TI HT KY. Contributed reagents/materials/analysis tools: TI HT MK KY. Wrote the paper: TI KY.