About the Authors

Satomi Iwai

Affiliation Laboratory of Small Animal Surgery I, School of Veterinary Medicine, Kitasato University, Aomori, Japan

Takeshi Kikuchi

Affiliation Center for Development of Advanced Medical Technology, Jichi Medical University, Tochigi, Japan

Naoya Kasahara

Affiliation Center for Development of Advanced Medical Technology, Jichi Medical University, Tochigi, Japan

Takumi Teratani

Affiliation Center for Development of Advanced Medical Technology, Jichi Medical University, Tochigi, Japan

Takashi Yokoo

Affiliation Project Laboratory for Kidney Regeneration, Institute of DNA Medicine, Department Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan

Iwao Sakonju

Affiliation Laboratory of Small Animal Surgery I, School of Veterinary Medicine, Kitasato University, Aomori, Japan

Shouzou Okano

Affiliation Laboratory of Small Animal Surgery II, School of Veterinary Medicine, Kitasato University, Aomori, Japan

Eiji Kobayashi

eijikoba@jichi.ac.jp

Affiliation Center for Development of Advanced Medical Technology, Jichi Medical University, Tochigi, Japan

Competing Interests

This study was funded by Otsuka Pharmaceutical Factory, Inc. (Naruto, Japan, http://www.otsukakj.jp/en/). EK is a chief scientific advisor at Otsuka Pharmaceutical Factory, Inc.. This not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SI EK. Performed the experiments: SI TK NK TT TY IS SO. Analyzed the data: SI. Contributed reagents/materials/analysis tools: SI TK TT EK. Wrote the paper: SI. Performed rat renal transplantations and obtained all samples about the rat renal transplantations model: SI. Pathological analysis: TY IS SO. Detection and quantification of transgene expression using a non-invasive in vivo imaging system: SI. Determination of fluorescence intensity of organ samples and measurement of ATP and ADP: TK. Measurement of kidney weight: NK.