About the Authors

Luisa Gatta

Contributed equally to this work with: Luisa Gatta, Fabiana Piscitelli

Affiliation Endocannabinoid Research Group, Department of Experimental Medicine–Division of Pharmacology “L. Donatelli”, Second University of Naples, Naples, Italy

Fabiana Piscitelli

Contributed equally to this work with: Luisa Gatta, Fabiana Piscitelli

Affiliation Endocannabinoid Research Group, Institute of Biomolecular Chemistry, C.N.R., Pozzuoli, Italy

Catia Giordano

Affiliation Endocannabinoid Research Group, Department of Experimental Medicine–Division of Pharmacology “L. Donatelli”, Second University of Naples, Naples, Italy

Serena Boccella

Affiliation Endocannabinoid Research Group, Department of Experimental Medicine–Division of Pharmacology “L. Donatelli”, Second University of Naples, Naples, Italy

Aron Lichtman

Affiliation Department of Pharmacology and Toxicology, Virginia Commonwealth University, School of Medicine, Richmond, Virginia, United States of America

Sabatino Maione

sabatino.maione@unina2.it (SM); vdimarzo@icmib.na.cnr.it (VD)

Affiliation Endocannabinoid Research Group, Department of Experimental Medicine–Division of Pharmacology “L. Donatelli”, Second University of Naples, Naples, Italy

Vincenzo Di Marzo

sabatino.maione@unina2.it (SM); vdimarzo@icmib.na.cnr.it (VD)

Affiliation Endocannabinoid Research Group, Institute of Biomolecular Chemistry, C.N.R., Pozzuoli, Italy

Competing Interests

This study was partly supported by Allergan, Irvine, CA, USA, and this does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: LG FP SM VD. Performed the experiments: LG FP CG SB. Analyzed the data: LG FP AL SM VD. Contributed reagents/materials/analysis tools: LG FP CG SB. Wrote the paper: AL SM VD.