About the Authors

Toshiyuki Sakaeda

sakaedat@pharm.kyoto-u.ac.jp (TS); okuno@pharm.kyoto-u.ac.jp (YO)

Affiliation Center for Development of Integrative Education in Pharmacy and Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan

Kaori Kadoyama

Affiliation Center for Development of Integrative Education in Pharmacy and Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan

Yasushi Okuno

sakaedat@pharm.kyoto-u.ac.jp (TS); okuno@pharm.kyoto-u.ac.jp (YO)

Affiliation Department of Systems Biosciences for Drug Discovery, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan

Competing Interests

YO, one of the authors, has a voluntary consultancy in Kyoto Constella Technologies Co., Ltd., Kyoto, Japan, concerning the business planning of the company. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials. The authors have declared that no other competing interests exist.

Author Contributions

Conceived and designed the experiments: TS KK YO. Performed the experiments: TS KK YO. Analyzed the data: YO. Contributed reagents/materials/analysis tools: YO. Wrote the paper: TS.