About the Authors

Jan R. Kraehling

Affiliation Department of Pharmacology, Toxicology and Clinical Pharmacy, University of Brunswick - Institute of Technology, Brunswick, Germany

Mareike Busker

Affiliation Department of Pharmacology, Toxicology and Clinical Pharmacy, University of Brunswick - Institute of Technology, Brunswick, Germany

Tobias Haase

Affiliation Berlin-Brandenburg Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Germany

Nadine Haase

Affiliation Experimental and Clinical Research Center and Max-Delbrück Center for Molecular Medicine, Berlin, Germany

Markus Koglin

Affiliation HEPTARES Therapeutics, Hertfordshire, United Kingdom

Monika Linnenbaum

Affiliation Department of Pharmacology, Toxicology and Clinical Pharmacy, University of Brunswick - Institute of Technology, Brunswick, Germany

Soenke Behrends

s.behrends@tu-braunschweig.de

Affiliation Department of Pharmacology, Toxicology and Clinical Pharmacy, University of Brunswick - Institute of Technology, Brunswick, Germany

Competing Interests

MK is currently employed at HEPTARES therapeutics, but the data used in the manuscript were obtained during his doctoral thesis under SB's mentorship at the University Medical Center Hamburg-Eppendorf. Due to this fact, this does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials..

Author Contributions

Conceived and designed the experiments: JRK SB. Performed the experiments: JRK MB TH ML. Analyzed the data: JRK SB. Contributed reagents/materials/analysis tools: NH MK. Wrote the paper: JRK SB.