About the Authors

Hung-Yu Sun

Affiliation Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan

Nai-Ying Ou

Affiliation Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, Tainan, Taiwan

Shainn-Wei Wang

Affiliation Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan

Wen-Chun Liu

Affiliation Department of Biotechnology, College of Applied Science, MingDao University, ChangHua, Taiwan

Ting-Fang Cheng

Affiliation Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan

Shiou-Jiuan Shr

Affiliation Department of Information and Learning Technology, Science and Engineering College, National University of Tainan, Tainan, Taiwan

Koun-Tem Sun

Affiliation Department of Information and Learning Technology, Science and Engineering College, National University of Tainan, Tainan, Taiwan

Ting-Tsung Chang

Affiliations Department of Internal Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan, Center of Infectious Disease and Signaling Research, National Cheng Kung University, Tainan, Taiwan

Kung-Chia Young

t7908077@mail.ncku.edu.tw

Affiliations Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan, Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, Tainan, Taiwan, Center of Infectious Disease and Signaling Research, National Cheng Kung University, Tainan, Taiwan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Obtained permission for use of replicon: KCY. Performed the bioinformatic analysis: SJS WCL. Performed the laboratory experiments: HYS NYO TFC. Conceived and designed the experiments: KCY. Analyzed the data: KCY. Contributed reagents/materials/analysis tools: KTS TTC SWW. Wrote the paper: KCY.