About the Authors

Richard A. Hubner

Affiliation Department of Medical Oncology, Christie NHS Foundation Trust, Manchester, United Kingdom

Richard D. Riley

Affiliation Department of Public Health, Epidemiology and Biostatistics, University of Birmingham, Birmingham, United Kingdom

Lucinda J. Billingham

Affiliations Cancer Research UK Clinical Trials Unit, University of Birmingham, Birmingham, United Kingdom, MRC Midland Hub for Trials Methodology Research, University of Birmingham, Birmingham, United Kingdom

Sanjay Popat

sanjay.popat@rmh.nhs.uk

Affiliations Department of Medicine, Royal Marsden NHS Foundation Trust, London, United Kingdom, Molecular Genetics Group, Imperial College, London, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RAH SP. Performed the experiments: RAH SP. Analyzed the data: RAH RDR LJB SP. Contributed reagents/materials/analysis tools: RAH RDR LJB SP. Wrote the paper: RAH RDR LJB SP.