About the Authors

Claudia Simm

t-ohalloran@northwestern.edu

Affiliation Chemistry of Life Processes Institute, Northwestern University, Evanston, Illinois, United States of America

Chi-Hao Luan

Affiliations Chemistry of Life Processes Institute, Northwestern University, Evanston, Illinois, United States of America, Department of Molecular Biosciences, Northwestern University, Evanston, Illinois, United States of America

Eric Weiss

Affiliations Chemistry of Life Processes Institute, Northwestern University, Evanston, Illinois, United States of America, Department of Molecular Biosciences, Northwestern University, Evanston, Illinois, United States of America

Thomas O'Halloran

Affiliations Chemistry of Life Processes Institute, Northwestern University, Evanston, Illinois, United States of America, Department of Molecular Biosciences, Northwestern University, Evanston, Illinois, United States of America, Department of Chemistry, Northwestern University, Evanston, Illinois, United States of America

Competing Interests

TVO is a consultant for and owns shares in Viamet Pharmaceuticals, Inc. which provided partial support for research expenses and research associate salary (CS) through a Research Agreement with Northwestern University. We know of no patent applications or commercial products related to the research described in this paper. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: CS. Performed the experiments: CS. Analyzed the data: CS C-HL. Contributed reagents/materials/analysis tools: CS C-HL TO. Wrote the paper: CS. Scientific discussion, data evaluation and editing of paper: EW TO.