About the Authors

Amanda A. Fox

afox@partners.org

Affiliation Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Mias Pretorius

Affiliation Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of Ameica

Kuang-Yu Liu

Affiliation Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Charles D. Collard

Affiliation Division of Cardiovascular Anesthesia at the Texas Heart Institute, Saint Luke's Episcopal Hospital, Houston, Texas, United States of America

Tjorvi E. Perry

Affiliation Northwest Anesthesia PA, Minneapolis, Minnesota, United States of America

Stanton K. Shernan

Affiliation Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Philip L. De Jager

Affiliation Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

David A. Hafler

Affiliation Department of Neurology, Yale School of Medicine, New Haven, Connecticut, United States of America

Daniel S. Herman

Affiliation Department of Genetics and Partners HealthCare Center for Genetics and Genomics, Harvard Medical School, Boston, Massachusetts, United States of America

Steven R. DePalma

Affiliation Department of Genetics and Partners HealthCare Center for Genetics and Genomics, Harvard Medical School, Boston, Massachusetts, United States of America

Dan M. Roden

Affiliation Departments of Medicine and Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Jochen D. Muehlschlegel

Affiliation Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Brian S. Donahue

Affiliation Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of Ameica

Dawood Darbar

Affiliation Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

J. G. Seidman

Affiliation Department of Genetics and Partners HealthCare Center for Genetics and Genomics, Harvard Medical School, Boston, Massachusetts, United States of America

Simon C. Body

Affiliation Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Christine E. Seidman

Affiliations Department of Genetics and Partners HealthCare Center for Genetics and Genomics, Harvard Medical School, Boston, Massachusetts, United States of America, Division of Cardiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Howard Hughes Medical Institute, Boston, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AF SB CC MP DR PDJ JS D. Herman CS K-YL SS. Performed the experiments: AF K-YL SB CS JS MP. Analyzed the data: AF K-YL D. Herman SB. Contributed reagents/materials/analysis tools: AF MP K-YL CC TP SS PDJ D. Hafler D. Herman SD DR JM BD DD JS SB CS. Wrote the paper: AF MP K-YL CC TP SS PDJ D. Herman SD DR JM BD DD JS SB CS.