About the Authors

Sebastian Virreira Winter

Current address: Department for Cellular Microbiology, Max Planck Institute for Infection Biology, Berlin, Germany

Affiliation Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America

Wendy Niedelman

Affiliation Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Kirk D. Jensen

Affiliation Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Emily E. Rosowski

Affiliation Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Lindsay Julien

Affiliation Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Eric Spooner

Affiliation Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America

Kacey Caradonna

Affiliation Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, United States of America

Barbara A. Burleigh

Affiliation Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, United States of America

Jeroen P. J. Saeij

Affiliation Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Hidde L. Ploegh

ploegh@wi.mit.edu (HLP); eva.frickel@nimr.mrc.ac.uk (E-MF)

Affiliations Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Eva-Maria Frickel

ploegh@wi.mit.edu (HLP); eva.frickel@nimr.mrc.ac.uk (E-MF)

Current address: Division of Parasitology, MRC National Institute for Medical Research, London, United Kingdom

Affiliation Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America

Competing Interests

Commercial funding has been received from Bayer HealthCare. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials. The authors have no patents or products in development or marketed products to declare.

Author Contributions

Conceived and designed the experiments: SVW JPJS HLP E-MF. Performed the experiments: SVW WN KDJ EER LJ ES KC E-MF. Analyzed the data: SVW JPJS HLP E-MF. Contributed reagents/materials/analysis tools: BAB. Wrote the paper: SVW HLP E-MF.