Generation of a Cell Culture-Adapted Hepatitis C Virus with Longer Half Life at Physiological Temperature

Chon Saeng Kim; Sun Ju Keum; Sung Key Jang

doi:10.1371/journal.pone.0022808

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Open Access

Peer-reviewed

Research Article

Generation of a Cell Culture-Adapted Hepatitis C Virus with Longer Half Life at Physiological Temperature

Chon Saeng Kim ,

Contributed equally to this work with: Chon Saeng Kim, Sun Ju Keum

Affiliation Molecular Virology Laboratory, POSTECH Biotech Center, Department of Life Science, Pohang University of Science and Technology, Pohang, Kyungbuk, Republic of Korea
⨯
Sun Ju Keum ,

Contributed equally to this work with: Chon Saeng Kim, Sun Ju Keum

Affiliation Molecular Virology Laboratory, POSTECH Biotech Center, Department of Life Science, Pohang University of Science and Technology, Pohang, Kyungbuk, Republic of Korea
⨯
Sung Key Jang

* E-mail: sungkey@postech.ac.kr

Affiliations Molecular Virology Laboratory, POSTECH Biotech Center, Department of Life Science, Pohang University of Science and Technology, Pohang, Kyungbuk, Republic of Korea, Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology, Pohang, Kyungbuk, Republic of Korea, Biotechnology Research Center, Pohang University of Science and Technology, Pohang, Kyungbuk, Republic of Korea
⨯

Generation of a Cell Culture-Adapted Hepatitis C Virus with Longer Half Life at Physiological Temperature

Chon Saeng Kim,
Sun Ju Keum,
Sung Key Jang

Published: August 4, 2011
https://doi.org/10.1371/journal.pone.0022808

About the Authors

Chon Saeng Kim

Contributed equally to this work with: Chon Saeng Kim, Sun Ju Keum

Affiliation Molecular Virology Laboratory, POSTECH Biotech Center, Department of Life Science, Pohang University of Science and Technology, Pohang, Kyungbuk, Republic of Korea

Sun Ju Keum

Contributed equally to this work with: Chon Saeng Kim, Sun Ju Keum

Affiliation Molecular Virology Laboratory, POSTECH Biotech Center, Department of Life Science, Pohang University of Science and Technology, Pohang, Kyungbuk, Republic of Korea

Sung Key Jang

* E-mail: sungkey@postech.ac.kr

Affiliations Molecular Virology Laboratory, POSTECH Biotech Center, Department of Life Science, Pohang University of Science and Technology, Pohang, Kyungbuk, Republic of Korea, Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology, Pohang, Kyungbuk, Republic of Korea, Biotechnology Research Center, Pohang University of Science and Technology, Pohang, Kyungbuk, Republic of Korea

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CSK SJK SKJ. Performed the experiments: CSK SJK. Analyzed the data: CSK SJK SKJ. Contributed reagents/materials/analysis tools: CSK SJK SKJ. Wrote the paper: CSK SJK SKJ.

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Microbial mutation
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Transfection
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Hepatitis C virus
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Virions
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Viral diseases
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Viral core
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Cloning
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Luciferase
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