About the Authors

Michael Absoud

michaelabsoud@childdemyelination.org.uk

Affiliation School of Health and Population Sciences, University of Birmingham, Birmingham, United Kingdom

Carole Cummins

Affiliation School of Health and Population Sciences, University of Birmingham, Birmingham, United Kingdom

Ming J. Lim

Affiliation Department of Paediatric Neurology, Evelina Children's Hospital at Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom

Evangeline Wassmer

Affiliation Department of Paediatric Neurology, Birmingham Children's Hospital NHS Foundation Trust, Birmingham, United Kingdom

Nick Shaw

Affiliation Department of Paediatric Endocrinology, Birmingham Children's Hospital NHS Foundation Trust, Birmingham, United Kingdom

Competing Interests

MA, CC, MJL, and EW are contributors to a prospective study of childhood CNS inflammatory demyelination funded by the MS Society and Action Medical Research (UK). The authors confirm that this does not alter adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MA NS. Performed the experiments: MA CC NS. Analyzed the data: MA CC. Contributed reagents/materials/analysis tools: MA CC ML EW NS. Wrote the paper: MA CC ML EW NS.