About the Authors

Ikuyo Kou

Affiliation Laboratory for Bone and Joint Diseases, Center for Genomic Medicine, RIKEN, Tokyo, Japan

Atsushi Takahashi

Affiliation Laboratory for Statistical Analysis, Center for Genomic Medicine, RIKEN, Tokyo, Japan

Tomohiko Urano

Affiliations Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, Department of Anti-Aging Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical University, Hidaka, Japan

Naoshi Fukui

Affiliation Department of Pathomechanisms, Clinical Research Center for Rheumatology and Allergy, National Hospital Organization Sagamihara National Hospital, Sagamihara, Japan

Hideki Ito

Affiliation Department of Internal Medicine, Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan

Kouichi Ozaki

Affiliation Laboratory for Cardiovascular Diseases, Center for Genomic Medicine, RIKEN, Yokohama, Japan

Toshihiro Tanaka

Affiliation Laboratory for Cardiovascular Diseases, Center for Genomic Medicine, RIKEN, Yokohama, Japan

Takayuki Hosoi

Affiliation Department of Advanced Medicine, National Center for Geriatrics and Gerontology, Obu, Japan

Masataka Shiraki

Affiliation Research Institute and Practice for Involutional Diseases, Azumino, Japan

Satoshi Inoue

Affiliations Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, Department of Anti-Aging Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical University, Hidaka, Japan

Yusuke Nakamura

Affiliations Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan, Laboratory for International Alliance, Center for Genomic Medicine, RIKEN, Yokohama, Japan

Naoyuki Kamatani

Affiliation Laboratory for Statistical Analysis, Center for Genomic Medicine, RIKEN, Tokyo, Japan

Michiaki Kubo

Affiliation Laboratory for Genotyping Development, Center for Genomic Medicine, RIKEN, Yokohama, Japan

Seijiro Mori

Affiliation Department of Internal Medicine, Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan

Shiro Ikegawa

sikegawa@ims.u-tokyo.ac.jp

Affiliation Laboratory for Bone and Joint Diseases, Center for Genomic Medicine, RIKEN, Tokyo, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: IK MK YN S. Ikegawa. Performed the experiments: IK TU MK. Analyzed the data: IK AT NK. Contributed reagents/materials/analysis tools: NF HI KO TT TH MS S. Inoue SM. Wrote the paper: IK.