About the Authors

Rima Matar-Merheb

Affiliation CNRS, Drug Resistance Mechanism and Modulation Laboratory, Ligue labeled team 2009, Lyon, France

Moez Rhimi

Contributed equally to this work with: Moez Rhimi, Antoine Leydier, Frédéric Huché

Affiliations CNRS, Drug Resistance Mechanism and Modulation Laboratory, Ligue labeled team 2009, Lyon, France, Laboratoire de BioCristallographie et Biologie Structurale des Cibles Thérapeutiques, Université Lyon 1, Univ Lyon; CNRS, UMR 5086; Bases Moléculaires et Structurales des Systèmes Infectieux, IBCP, Lyon, France

Antoine Leydier

Contributed equally to this work with: Moez Rhimi, Antoine Leydier, Frédéric Huché

Affiliation CEA DEN/DRCP/SCPS/LEPS, Bagnols-sur-Cèze, France

Frédéric Huché

Contributed equally to this work with: Moez Rhimi, Antoine Leydier, Frédéric Huché

Affiliations CNRS, Drug Resistance Mechanism and Modulation Laboratory, Ligue labeled team 2009, Lyon, France, Laboratoire de BioCristallographie et Biologie Structurale des Cibles Thérapeutiques, Université Lyon 1, Univ Lyon; CNRS, UMR 5086; Bases Moléculaires et Structurales des Systèmes Infectieux, IBCP, Lyon, France

Carmen Galián

Affiliation CNRS/CEA/Université Joseph Fourier, Institut de Biologie Structurale, Grenoble, France

Elodie Desuzinges-Mandon

Affiliation CNRS, Drug Resistance Mechanism and Modulation Laboratory, Ligue labeled team 2009, Lyon, France

Damien Ficheux

Affiliation CNRS, Drug Resistance Mechanism and Modulation Laboratory, Ligue labeled team 2009, Lyon, France

David Flot

Affiliation European Synchrotron Radiation Facility, BP 220, Grenoble, France

Nushin Aghajari

Affiliation Laboratoire de BioCristallographie et Biologie Structurale des Cibles Thérapeutiques, Université Lyon 1, Univ Lyon; CNRS, UMR 5086; Bases Moléculaires et Structurales des Systèmes Infectieux, IBCP, Lyon, France

Richard Kahn

Affiliation CNRS/CEA/Université Joseph Fourier, Institut de Biologie Structurale, Grenoble, France

Attilio Di Pietro

Affiliation CNRS, Drug Resistance Mechanism and Modulation Laboratory, Ligue labeled team 2009, Lyon, France

Jean-Michel Jault

Affiliation CNRS/CEA/Université Joseph Fourier, Institut de Biologie Structurale, Grenoble, France

Anthony W. Coleman

p.falson@ibcp.fr (PF); anthony.coleman@univ-lyon1.fr (AWC)

Affiliation Laboratoire des Multimatériaux et Interfaces, UMR 5615 CNRS/Université de Lyon 1, Lyon, France

Pierre Falson

p.falson@ibcp.fr (PF); anthony.coleman@univ-lyon1.fr (AWC)

Affiliation CNRS, Drug Resistance Mechanism and Modulation Laboratory, Ligue labeled team 2009, Lyon, France

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AWC J-MJ PF. Performed the experiments: RM-M MR AL FH CG ED-M D. Ficheux D. Flot RK J-MJ PF. Analyzed the data: PF AWC J-MJ RK NA ADP. Wrote the paper: PF AWC NA J-MJ.