About the Authors

Philip Stegmaier

Affiliation BIOBASE GmbH, Wolfenbuettel, Germany

Nico Voss

Affiliation BIOBASE GmbH, Wolfenbuettel, Germany

Tatiana Meier

Affiliations Department Molecular Medicine and Medical Biotechnology, Fraunhofer Institute of Toxicology and Experimental Medicine, Hannover, Germany, Centre for Pharmacology and Toxicology, Hannover Medical School, Hannover, Germany

Alexander Kel

Affiliations BIOBASE GmbH, Wolfenbuettel, Germany, GeneXplain GmbH, Wolfenbuettel, Germany, Institute of Chemical Biology and Fundamental Medicine, Novosibirsk, Russia

Edgar Wingender

Affiliations BIOBASE GmbH, Wolfenbuettel, Germany, GeneXplain GmbH, Wolfenbuettel, Germany, Department of Bioinformatics, University of Goettingen, Goettingen, Germany

Juergen Borlak

juergen.borlak@item.fraunhofer.de

Affiliations Department Molecular Medicine and Medical Biotechnology, Fraunhofer Institute of Toxicology and Experimental Medicine, Hannover, Germany, Centre for Pharmacology and Toxicology, Hannover Medical School, Hannover, Germany

Competing Interests

PS, NV, AK, EW and JB are employees of BIOBASE GmbH, Wolfenbuettel, Germany. AK is also an employee of Institute of Systems Biology Ltd., Novosibirsk, Russia. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials, as detailed online in your guide for authors.

Author Contributions

Conceived and designed the experiments: JB. Performed the experiments: TM JB. Analyzed the data: PS TM AK EW JB. Contributed reagents/materials/analysis tools: JB. Wrote the paper: PS AK JB.