About the Authors

Espen Enerly

Contributed equally to this work with: Espen Enerly, Israel Steinfeld

Affiliations Division of Surgery and Cancer, Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway

Israel Steinfeld

Contributed equally to this work with: Espen Enerly, Israel Steinfeld

Affiliation Department of Computer Science, Technion, Haifa, Israel

Kristine Kleivi

Affiliations Division of Surgery and Cancer, Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway, Medical Biotechnology, VTT Technical Research Centre of Finland, Turku, Finland

Suvi-Katri Leivonen

Affiliation Medical Biotechnology, VTT Technical Research Centre of Finland, Turku, Finland

Miriam R. Aure

Affiliation Division of Surgery and Cancer, Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway

Hege G. Russnes

Affiliations Division of Surgery and Cancer, Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway, Division of Pathology, Oslo University Hospital, Oslo, Norway

Jo Anders Rønneberg

Affiliations Division of Surgery and Cancer, Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway

Hilde Johnsen

Affiliation Division of Surgery and Cancer, Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway

Roy Navon

Affiliation Agilent Laboratories, Tel Aviv, Israel

Einar Rødland

Affiliation Department of Informatics, University of Oslo, Oslo, Norway

Rami Mäkelä

Affiliation Medical Biotechnology, VTT Technical Research Centre of Finland, Turku, Finland

Bjørn Naume

Affiliation Division of Surgery and Cancer, Department of Oncology, Oslo University Hospital, Oslo, Norway

Merja Perälä

Affiliation Medical Biotechnology, VTT Technical Research Centre of Finland, Turku, Finland

Olli Kallioniemi

Affiliations Medical Biotechnology, VTT Technical Research Centre of Finland, Turku, Finland, Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland

Vessela N. Kristensen

Affiliations Division of Surgery and Cancer, Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway, Institute for Clinical Epidemiology and Molecular Biology (EPIGEN), Nordbyhagen, Norway

Zohar Yakhini

zohar_yakhini@agilent.com (ZY); a.l.borresen-dale@medisin.uio.no (A-LB-D)

Affiliations Department of Computer Science, Technion, Haifa, Israel, Agilent Laboratories, Tel Aviv, Israel

Anne-Lise Børresen-Dale

zohar_yakhini@agilent.com (ZY); a.l.borresen-dale@medisin.uio.no (A-LB-D)

Affiliations Division of Surgery and Cancer, Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway

Competing Interests

ZY and RN are employed by Agilent Technologies. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: EE IS OK VNK ZY A-LB-D. Performed the experiments: EE KK S-KL MRA HGR JAR HJ RM BN MP. Analyzed the data: IS EE RN ER. Wrote the manuscript: EE IS OK VNK ZY A-LB-D. Designed computational tools used in analysis: IS ZY.