About the Authors

Ralph Carvalho

Contributed equally to this work with: Ralph Carvalho, Jan de Sonneville

h.p.spaink@biology.leidenuniv.nl

Affiliations ZF-screens B.V., Leiden, The Netherlands, Institute of Biology, Leiden University, Leiden, The Netherlands

Jan de Sonneville

Contributed equally to this work with: Ralph Carvalho, Jan de Sonneville

Affiliation Institute of Chemistry, Leiden University, Leiden, The Netherlands

Oliver W. Stockhammer

Affiliation Institute of Biology, Leiden University, Leiden, The Netherlands

Nigel D. L. Savage

Affiliation Department of Immunohematology and Blood Transfusion, Leiden University Medical Centre, Leiden, The Netherlands

Wouter J. Veneman

Affiliation Institute of Biology, Leiden University, Leiden, The Netherlands

Tom H. M. Ottenhoff

Affiliation Department of Immunohematology and Blood Transfusion, Leiden University Medical Centre, Leiden, The Netherlands

Ron P. Dirks

Affiliation ZF-screens B.V., Leiden, The Netherlands

Annemarie H. Meijer

Affiliation Institute of Biology, Leiden University, Leiden, The Netherlands

Herman P. Spaink

Affiliation Institute of Biology, Leiden University, Leiden, The Netherlands

Competing Interests

Co-authors R.C. and R.P.D are employees of ZF-screens B.V. and played a role in the study design, data collection and analysis, decision to publish and preparation of the manuscript. The decision to publish was approved by the Directors of ZF-screens B.V., and no other employees have had any involvement in the study. Further, ZF-screens B.V. is the co-owner of a patent application (EP09164956.6) on this subject matter. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: RC JS OWS NDLS RPD AHM HPS. Performed the experiments: RC JS OWS NDLS WJV. Analyzed the data: RC JS OWS WJV. Contributed reagents/materials/analysis tools: THMO RPD AHM HPS. Wrote the paper: RC JS NDLS THMO AHM HPS. Designed and assembled automatic injection system: JS. Designed the software for the injection system: JS.