About the Authors

Shiaw-Wei Tyan

Affiliation Genomics Research Center, Academia Sinica, Taipei, Taiwan Authority

Wen-Hung Kuo

Affiliation Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan Authority

Chun-Kai Huang

Affiliation Genomics Research Center, Academia Sinica, Taipei, Taiwan Authority

Chi-Chun Pan

Affiliation Genomics Research Center, Academia Sinica, Taipei, Taiwan Authority

Jin-Yuh Shew

Affiliation Genomics Research Center, Academia Sinica, Taipei, Taiwan Authority

King-Jen Chang

kingjen@ntu.edu.tw (K-JC); elee@uci.edu (EY-HPL); whlee@uci.edu (W-HL)

Affiliation Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan Authority

Eva Y.-H. P. Lee

kingjen@ntu.edu.tw (K-JC); elee@uci.edu (EY-HPL); whlee@uci.edu (W-HL)

Affiliations Genomics Research Center, Academia Sinica, Taipei, Taiwan Authority, Department of Development and Cell Biology, University of California Irvine, Irvine, California, United States of America, Department of Biological Chemistry, University of California Irvine, Irvine, California, United States of America

Wen-Hwa Lee

kingjen@ntu.edu.tw (K-JC); elee@uci.edu (EY-HPL); whlee@uci.edu (W-HL)

Affiliations Genomics Research Center, Academia Sinica, Taipei, Taiwan Authority, Department of Biological Chemistry, University of California Irvine, Irvine, California, United States of America

Competing Interests

Based on University of California Irvine policy, WHL and EL declare that they have financial interests of a biotech company, GeneTex, which distributes research reagents globally and owns stock from Schering-Plough, a publicly traded pharmaceutical company, like any stockholder. WHL is on the board of directors, and EL is a consultant. GeneTex did not support this work in any way. These data and material will be distributed freely following the policies of PLoS ONE. It is the authors' recognition that these financial interests could not generate any bias toward this work, and do not alter their adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: S-WT J-YS EY-HPL W-HL. Performed the experiments: S-WT C-KH C-CP. Analyzed the data: S-WT C-KH C-CP. Contributed reagents/materials/analysis tools: W-HK K-JC. Wrote the paper: S-WT EY-HPL W-HL.