About the Authors

Oleg Chertov

Affiliation Protein Chemistry Laboratory, Advanced Technology Program, SAIC-Frederick, Inc., National Cancer Institute at Frederick, Frederick, Maryland, United States of America

Ning Zhang

Affiliation Laboratory of Molecular Immunoregulation, National Cancer Institute at Frederick, Frederick, Maryland, United States of America

Xin Chen

Affiliation Laboratory of Molecular Immunoregulation, National Cancer Institute at Frederick, Frederick, Maryland, United States of America

Joost J. Oppenheim

Affiliation Laboratory of Molecular Immunoregulation, National Cancer Institute at Frederick, Frederick, Maryland, United States of America

Jacek Lubkowski

Affiliation Macromolecular Crystallography Laboratory, National Cancer Institute at Frederick, Frederick, Maryland, United States of America

Connor McGrath

Affiliation Target Structure-Based Drug Discovery Group, Frederick, Maryland, United States of America

Raymond C. Sowder II

Affiliation AIDS and Cancer Virus Program, SAIC-Frederick, Inc., Frederick, Maryland, United States of America

Bruce J. Crise

Affiliation AIDS and Cancer Virus Program, SAIC-Frederick, Inc., Frederick, Maryland, United States of America

Anatoli Malyguine

Affiliation Clinical Services Program, SAIC-Frederick, Inc., Frederick, Maryland, United States of America

Michele A. Kutzler

Affiliation Department of Pharmacology, Fels Institute for Cancer Research and Molecular Biology, Center for Substance Abuse Research, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America

Amber D. Steele

Affiliation Department of Pharmacology, Fels Institute for Cancer Research and Molecular Biology, Center for Substance Abuse Research, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America

Earl E. Henderson

Affiliation Department of Pharmacology, Fels Institute for Cancer Research and Molecular Biology, Center for Substance Abuse Research, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America

Thomas J. Rogers

rogerst@temple.edu

Affiliation Department of Pharmacology, Fels Institute for Cancer Research and Molecular Biology, Center for Substance Abuse Research, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America

Competing Interests

Several of the authors are employed by the National Institutes of Health (NIH), and the NIH was a sponsor of the research work. This does not alter the authors' adherence to all of the PLoS ONE policies on sharing of data and materials.

Author Contributions

Conceived and designed the experiments: OC JO EH TJR. Performed the experiments: OC NZ XC JL CM MAK AS TJR. Analyzed the data: OC JL CM RSI BC AM TJR. Contributed reagents/materials/analysis tools: OC JL CM RSI TJR. Wrote the paper: OC TJR.