About the Authors

Rhea N. Coler

Contributed equally to this work with: Rhea N. Coler, Susan L. Baldwin

Affiliation Infectious Disease Research Institute, Seattle, Washington, United States of America

Susan L. Baldwin

Contributed equally to this work with: Rhea N. Coler, Susan L. Baldwin

Affiliation Infectious Disease Research Institute, Seattle, Washington, United States of America

Narek Shaverdian

Affiliation Infectious Disease Research Institute, Seattle, Washington, United States of America

Sylvie Bertholet

Affiliation Infectious Disease Research Institute, Seattle, Washington, United States of America

Steven J. Reed

Affiliation Infectious Disease Research Institute, Seattle, Washington, United States of America

Vanitha S. Raman

Affiliation Infectious Disease Research Institute, Seattle, Washington, United States of America

Xiuhua Lu

Affiliation National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

Joshua DeVos

Affiliation National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

Kathy Hancock

Affiliation National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

Jacqueline M. Katz

Affiliation National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

Thomas S. Vedvick

Affiliation Infectious Disease Research Institute, Seattle, Washington, United States of America

Malcolm S. Duthie

Affiliation Infectious Disease Research Institute, Seattle, Washington, United States of America

Christopher H. Clegg

Affiliation Immune Design Corporation, Seattle, Washington, United States of America

Neal Van Hoeven

Affiliation Immune Design Corporation, Seattle, Washington, United States of America

Steven G. Reed

sreed@idri.org

Affiliations Infectious Disease Research Institute, Seattle, Washington, United States of America, Immune Design Corporation, Seattle, Washington, United States of America

Competing Interests

Dr. Steven G. Reed is a founder of, and holds an equity interest in, Immune Design Corporation, a licensee of certain rights associated with GLA. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: RC SB CHC SGR. Performed the experiments: NS SJR VSR XL JD MSD NVH. Analyzed the data: RC SB NS SB. Contributed reagents/materials/analysis tools: TSV. Wrote the paper: RC SB NS SB. Edited the manuscript: KH JMK SGR.