About the Authors

Ming-Hsi Huang

huangminghsi@nhri.org.tw (M-HH); pelechong@nhri.org.tw (PC)

Affiliation Vaccine Research and Development Center, National Health Research Institutes, Zhunan Town, Taiwan

Su-Chen Lin

Affiliation Vaccine Research and Development Center, National Health Research Institutes, Zhunan Town, Taiwan

Chia-Hsin Hsiao

Affiliation Vaccine Research and Development Center, National Health Research Institutes, Zhunan Town, Taiwan

Hsin-Ju Chao

Affiliation Vaccine Research and Development Center, National Health Research Institutes, Zhunan Town, Taiwan

Hung-Ren Yang

Affiliation Vaccine Research and Development Center, National Health Research Institutes, Zhunan Town, Taiwan

Chien-Chun Liao

Affiliation Vaccine Research and Development Center, National Health Research Institutes, Zhunan Town, Taiwan

Po-Wei Chuang

Affiliation Vaccine Research and Development Center, National Health Research Institutes, Zhunan Town, Taiwan

Huang-Pi Wu

Affiliation Vaccine Research and Development Center, National Health Research Institutes, Zhunan Town, Taiwan

Chiung-Yi Huang

Affiliation Vaccine Research and Development Center, National Health Research Institutes, Zhunan Town, Taiwan

Chih-Hsiang Leng

Affiliation Vaccine Research and Development Center, National Health Research Institutes, Zhunan Town, Taiwan

Shih-Jen Liu

Affiliation Vaccine Research and Development Center, National Health Research Institutes, Zhunan Town, Taiwan

Hsin-Wei Chen

Affiliation Vaccine Research and Development Center, National Health Research Institutes, Zhunan Town, Taiwan

Ai-Hsiang Chou

Affiliation Vaccine Research and Development Center, National Health Research Institutes, Zhunan Town, Taiwan

Alan Yung-Chih Hu

Affiliation Vaccine Research and Development Center, National Health Research Institutes, Zhunan Town, Taiwan

Pele Chong

huangminghsi@nhri.org.tw (M-HH); pelechong@nhri.org.tw (PC)

Affiliation Vaccine Research and Development Center, National Health Research Institutes, Zhunan Town, Taiwan

Competing Interests

MHH, PC, CHL, SJL, HWC are named on a patent relating to the preparation and use of multi-phase emulsions based on amphiphilic block copolymers. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials. All other authors have no conflict of interest.

Author Contributions

Conceived and designed the experiments: MHH PC. Performed the experiments: MHH SCL HJC HRY PWC CYH AHC. Analyzed the data: MHH. Contributed reagents/materials/analysis tools: MHH CHH CCL HPW CHL SJL HWC AYCH. Wrote the paper: MHH. Contributed to establishment of the cGMP facility: CHH CHL AHC PC. Managed the whole project: PC.