About the Authors

Shihoko Kojima

Affiliations Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America, Department of Biology, University of Virginia, Charlottesville, Virginia, United States of America

David Gatfield

Affiliation Department of Molecular Biology, University of Geneva, Geneva, Switzerland

Christine C. Esau

Affiliation Regulus Therapeutics, Carlsbad, California, United States of America

Carla B. Green

Carla.Green@utsouthwestern.edu

Affiliations Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America, Department of Biology, University of Virginia, Charlottesville, Virginia, United States of America

Competing Interests

Carla Green serves on the Scientific Advisory Board of ReSet Therapeutics, Inc. Christine Esau is employed by Regulus Therapeutics, but the reagent contributed to this study is available to the scientific community through an MTA and is not under clinical development. These interests do not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SK DG CBG. Performed the experiments: SK DG. Analyzed the data: SK DG. Contributed reagents/materials/analysis tools: SK DG CE. Wrote the paper: SK CBG.