About the Authors
- Shigeru Nakamura
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Affiliations Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan, Research Center, Ophtecs Corporation, Toyooka, Japan
- Shigeru Kinoshita
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Affiliation Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
- Norihiko Yokoi
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Affiliation Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
- Yoko Ogawa
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Affiliation Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan
- Michiko Shibuya
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Affiliation Research Center, Ophtecs Corporation, Toyooka, Japan
- Hideo Nakashima
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Affiliations Research Center, Ophtecs Corporation, Toyooka, Japan, Department of Veterinary Anatomy, Faculty of Agriculture, Tottori University, Tottori, Japan
- Ryuji Hisamura
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Affiliation Research Center, Ophtecs Corporation, Toyooka, Japan
- Toshihiro Imada
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Affiliation Research Center, Ophtecs Corporation, Toyooka, Japan
- Tomohiro Imagawa
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Affiliation Department of Veterinary Anatomy, Faculty of Agriculture, Tottori University, Tottori, Japan
- Masato Uehara
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Affiliation Department of Veterinary Anatomy, Faculty of Agriculture, Tottori University, Tottori, Japan
- Izumi Shibuya
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Affiliation Department of Veterinary Physiology, Faculty of Agriculture, Tottori University, Tottori, Japan
- Murat Dogru
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Affiliation Johnson & Johnson Ocular Surface Visual Optics Department, Keio University School of Medicine, Tokyo, Japan
- Samantha Ward
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Affiliation Johnson & Johnson Ocular Surface Visual Optics Department, Keio University School of Medicine, Tokyo, Japan
- Kazuo Tsubota
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* E-mail: tsubota@sc.itc.keio.ac.jp
Affiliation Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
Conceived and designed the experiments: SN SK NY MS HN RH T. Imada MD SW KT. Performed the experiments: MS HN RH T. Imada MD SW. Analyzed the data: SN SK NY MS HN RH T. Imada MD. Wrote the paper: SN SK MD SW KT. Designed the epidemiological study and analyzed the data, and wrote the corresponding part: SK NY MD SW. Performed the clinical portion of the human study and electron microscopy: YO. Performed the pathological analysis of the animal study: T. Imagawa MU. Performed the exocrine analysis of the animal study: IS.