About the Authors
- Akihiro Higuchi
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* E-mail: ahiguchi@sc.itc.keio.ac.jp
Affiliation Center for Integrated Medical Research, School of Medicine, Keio University, Tokyo, Japan
- Kazuhiko Takahashi
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Affiliation Department of Nutritional Biochemistry, School of Pharmacy, Hokkaido Pharmaceutical University, Hokkaido, Japan
- Masaki Hirashima
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Affiliation Research Department 1, The Chemo-Sero-Therapeutic Research Institute, Kumamoto, Japan
- Tetsuya Kawakita
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Affiliation Department of Ophthalmology, School of Medicine, Keio University, Tokyo, Japan
- Kazuo Tsubota
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Affiliations Center for Integrated Medical Research, School of Medicine, Keio University, Tokyo, Japan, Department of Ophthalmology, School of Medicine, Keio University, Tokyo, Japan
Competing Interests
The authors do not have any duty for their research to Kowa Company except sharing products from their research. The authors have already applied for a patent on selenoprotein P to apply the treatment of dry eye ((WO 2006/137426) PROPHYLACTIC OR THERAPEUTIC AGENT FOR CORNEAL/CONJUNCTIVAL DISEASE). The authors do not have any relationship with Kowa Company for employment or consultancy. The authors declare that this does not alter their adherence to all the PLoS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: AH TK KT. Performed the experiments: AH. Analyzed the data: AH. Contributed reagents/materials/analysis tools: AH KT MH. Wrote the paper: AH KT.