About the Authors

James C. Stevens

Contributed equally to this work with: James C. Stevens, Ruth Chia

Affiliation Department of Neurodegenerative Disease, UCL Institute of Neurology, London, United Kingdom

Ruth Chia

Contributed equally to this work with: James C. Stevens, Ruth Chia

Affiliation Department of Neurodegenerative Disease, UCL Institute of Neurology, London, United Kingdom

William T. Hendriks

Affiliation Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Virginie Bros-Facer

Affiliation Sobell Department of Motor Science and Movement Disorders, UCL Institute of Neurology, London, United Kingdom

Jan van Minnen

Affiliation Department of Cell Biology and Anatomy, Hotchkiss Brain Institute, University of Calgary, Calgary, Canada

Joanne E. Martin

Affiliation ICMS Pathology Group, Queen Mary University of London, London, United Kingdom

Graham S. Jackson

Affiliation MRC Prion Unit, UCL Institute of Neurology, London, United Kingdom

Linda Greensmith

Affiliation Sobell Department of Motor Science and Movement Disorders, UCL Institute of Neurology, London, United Kingdom

Giampietro Schiavo

Affiliation Molecular Neuropathobiology Laboratory, Cancer Research UK, London, United Kingdom

Elizabeth M. C. Fisher

e.fisher@prion.ucl.ac.uk

Affiliation Department of Neurodegenerative Disease, UCL Institute of Neurology, London, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JS RC WTH VBF JvM JM GSJ LG GS EMF. Performed the experiments: JS RC WTH. Analyzed the data: JS RC. Contributed reagents/materials/analysis tools: JS RC WTH VBF EMF. Wrote the paper: JS RC EMF.