About the Authors

Etsuko Miyamoto-Sato

hyana@bio.keio.ac.jp (HY); nekoneko@educ.cc.keio.ac.jp (EM-S)

Affiliations Advanced Research Centers, Keio University, Yokohama, Japan, Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University, Yokohama, Japan

Shigeo Fujimori

Affiliation Advanced Research Centers, Keio University, Yokohama, Japan

Masamichi Ishizaka

Affiliation Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University, Yokohama, Japan

Naoya Hirai

Affiliation Advanced Research Centers, Keio University, Yokohama, Japan

Kazuyo Masuoka

Affiliation Advanced Research Centers, Keio University, Yokohama, Japan

Rintaro Saito

Affiliation Department of Environment and Information Studies, Keio University, Fujisawa, Japan

Yosuke Ozawa

Affiliation Systems Biology Program, Graduate School of Media and Governance, Keio University, Fujisawa, Japan

Katsuya Hino

Affiliations Advanced Research Centers, Keio University, Yokohama, Japan, Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University, Yokohama, Japan

Takanori Washio

Affiliation Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University, Yokohama, Japan

Masaru Tomita

Affiliation Department of Environment and Information Studies, Keio University, Fujisawa, Japan

Tatsuhiro Yamashita

Affiliations Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University, Yokohama, Japan, BioIT Business Development Unit, Fujitsu Limited, Chiba, Japan

Tomohiro Oshikubo

Affiliations Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University, Yokohama, Japan, Production Solution Business Unit, Production Solution Division, Solutions and Services Department, Fujitsu Advanced Engineering Limited, Tokyo, Japan

Hidetoshi Akasaka

Affiliations Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University, Yokohama, Japan, Production Solution Business Unit, Production Solution Division, Solutions and Services Department, Fujitsu Advanced Engineering Limited, Tokyo, Japan

Jun Sugiyama

Affiliations Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University, Yokohama, Japan, Special Suite Team, Custom Primer Production Department, Haneda Laboratories, Invitrogen Japan K.K., Tokyo, Japan

Yasuo Matsumoto

Affiliations Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University, Yokohama, Japan, Automation, QIAGEN K.K., Tokyo, Japan

Hiroshi Yanagawa

hyana@bio.keio.ac.jp (HY); nekoneko@educ.cc.keio.ac.jp (EM-S)

Affiliations Advanced Research Centers, Keio University, Yokohama, Japan, Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University, Yokohama, Japan

Competing Interests

Some of the authors are company employees of BioIT Business Development Unit, Fujitsu Limited; Production Solution Business Unit, Production Solution Division, Solutions and Services Department, Solution Section, Fujitsu Advanced Engineering Limited; Special Suite Team, Custom Primer Production Department, Invitrogen Japan K.K.; and Automation, QIAGEN K.K.. But the companies did not fund the study of this work, and no patents or commercial products were newly produced in this work.

Author Contributions

Conceived and designed the experiments: EMS. Performed the experiments: MI NH KM KH JS YM. Analyzed the data: SF RS YO TW MT TY TO HA. Wrote the paper: EMS MI SF RS. Directed the project: HY. Sub-directed the project: EMS.