About the Authors

Georgina Thorborn

Affiliation Department of Infectious Diseases, King's College London, Guys' Hospital, London, England

Laura Pomeroy

Affiliation Department of Infectious Diseases, King's College London, St Thomas' Hospital, London, England

Heidi Isohanni

Affiliation Department of Infectious Diseases, King's College London, St Thomas' Hospital, London, England

Melissa Perry

Affiliation Department of Infectious Diseases, King's College London, St Thomas' Hospital, London, England

Barry Peters

Contributed equally to this work with: Barry Peters, Annapurna Vyakarnam

Affiliation Department of Infectious Diseases, King's College London, St Thomas' Hospital, London, England

Annapurna Vyakarnam

Contributed equally to this work with: Barry Peters, Annapurna Vyakarnam

anna.Vyakarnam@kcl.ac.uk

Affiliation Department of Infectious Diseases, King's College London, Guys' Hospital, London, England

Competing Interests

This work was partly supported by an educational grant from Gilead Pharmaceuticals. This does not alter the authors' adherence to all the PLOS One policies on sharing data and materials, as detailed in the online guide for authors.

Author Contributions

Conceived and designed the experiments: GT AV. Performed the experiments: GT AV. Analyzed the data: GT AV. Contributed reagents/materials/analysis tools: LP HI MP BP AV. Wrote the paper: GT AV.